The symptoms of arthritis usually occur in the prodromal stage of the disease and could be without any other clinical manifestations of hepatitis. The presence of rash and fever may provide clues to the underlying diagnosis. Immune complex formation and deposition are also considered the pathophysiologic mechanism for arthritis in patients with hepatitis C. HIV : The arthritis syndromes associated with HIV include many entities such as HIV-associated arthritis, reactive arthritis, septic arthritis, psoriatic arthritis, and rarely described painful articular syndrome.
EBV : Arthralgias are the most common joint manifestation of Epstein-Barr viral infection, with the rare case of arthritis causing occasional large joint swelling.
The joint signs and symptoms are self-limited, and treatment is symptomatic. A triggering role in the development of chronic inflammatory arthritis in RA has been proposed, but no definite evidence has been found. Alphaviruses : These viruses are mosquito-borne RNA viruses that cause epidemics of febrile arthralgia and polyarthritis. The most notable is CHIKV which has become very important in recent times with regards to global health and travel.
The arthritis of CHIKV is typically symmetrical and most commonly involves the fingers, wrists, knees, and ankles. Raynaud phenomenon has been reported as well in some patients. Flaviviruses : Dengue and Zika virus are prominent members of this group causing febrile illnesses and symptoms of joint pain and swelling.
As with the above-mentioned alphaviruses, the geographical distribution of these viruses has significantly expanded in recent times. Aedes aegypti is the principle vector for Dengue. Zika virus, known for its association with congenital microcephaly and fetal losses among women infected during pregnancy, also manifests with joint symptoms. Other viruses : Mumps, HTLV-1, rubella, and some enteroviruses can also cause arthralgia and arthritis.
Differential Diagnosis Lupus. Prognosis Viral arthritis is a mild self-limited disorder in most people. Enhancing Healthcare Team Outcomes Because of the difficulty in diagnosis, the disorder is best managed by an interprofessional team. Review Questions Access free multiple choice questions on this topic. Comment on this article. References 1.
The molecular and cellular aspects of arthritis due to alphavirus infections: lesson learned from Ross River virus. Ann N Y Acad Sci. Moore TL. Parvovirus-associated arthritis. Curr Opin Rheumatol. Kerr JR. Pathogenesis of human parvovirus B19 in rheumatic disease. Ann Rheum Dis. The pathogenesis of arthritis associated with acute hepatitis-B surface antigen-positive hepatitis. Complement activation and characterization of circulating immune complexes. J Clin Invest.
Ganem D, Prince AM. Hepatitis B virus infection--natural history and clinical consequences. N Engl J Med. Arthritis in viral hepatitis. Report of two cases and review of the literature. Johns Hopkins Med J. Extrahepatic manifestations of chronic HCV infection. J Gastrointestin Liver Dis. J Gen Virol, Virology, 2 Arbovirus Res Aust Aust Equine Vet Clin Exp Immunol, 1 Med J Aust, 7 J Med Entomol, 2 Viruses , 13 6 , 31 May Front Immunol , , 14 Jul J Rheumatol , 47 8 , 01 Jul Free to read.
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Europe PMC requires Javascript to function effectively. Recent Activity. Search life-sciences literature Over 39 million articles, preprints and more Search Advanced search. Proceedings of the National Academy of Sciences. National Acad Sciences; ;—5. Isolation of virus strains from mosquitoes collected in Queensland, A comparison of the diseases caused by Ross River virus and Barmah Forest virus. The Medical Journal of Australia. Journal of General Virology. PloS one.
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The American journal of tropical medicine and hygiene. ASTMH; ;— Australian and New Zealand journal of public health. Wiley Online Library; ;— Arboviral diseases and malaria in Australia, annual report of the National Arbovirus and Malaria Advisory Committee.
Nucleotide sequence of the Barmah Forest virus genome. Elsevier; ;— Viruses recovered from mosquitoes and wildlife serum collected in the Murray Valley of south-eastern Australia, February , during an epidemic of encephalitis. McMichael A. Global climate change: will it affect vector-borne infectious diseases? Internal medicine journal. Intern Med J. In the latter case, please turn on Javascript support in your web browser and reload this page. Read article at publisher's site DOI : Am J Trop Med Hyg, 5 Annu Rev Immunol, J Gen Virol, Virology, 2 Arbovirus Res Aust Aust Equine Vet Clin Exp Immunol, 1 Med J Aust, 7 J Med Entomol, 2 Viruses , 13 6 , 31 May Front Immunol , , 14 Jul J Rheumatol , 47 8 , 01 Jul Free to read.
To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation. Aust Fam Physician , 38 8 , 01 Aug Cited by: 10 articles PMID: Vaccine , 29 24 , 06 Apr Cited by: 21 articles PMID: Trop Med Int Health , 13 7 , 13 May Cited by: 22 articles PMID: Cited by: 35 articles PMID: Microbes Infect , 19 11 , 25 Jul
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